Nicholas C. Bauer PhD
Cellular, Molecular, and Computational Biologist
Postdoctoral Research Fellow
Massachusetts General Hospital and Harvard Medical School
Harnessing advanced microscopy and computational analyses to extract information on the relationships and dynamics of molecules in their native cellular contexts.
Improving the quality and usability of scientific software.
More open, collaborative science.
PhD, Biological and Biomedical Sciences, Emory University
BS, Program in Biological Chemistry, Bates College
Certificate, Software Engineering, Harvard University
Hemocytometer Sidekick - Easier cell counting with a hemocytometer. Available in iOS/Android/Windows app stores. Source not yet public.
SimpleANOVA.jl - Analysis of Variance package for the Julia language, for those who prefer to stay away from linear models.
Q-SCAn - Package implementing Quantitative Subcellular Compartmentalization Analysis developed for use with Cell Profiler and ImageJ to quantify the distribution of a protein among cellular compartments.
Scryptonite - Built the scrypt cryptographic algorithm from the source paper and released it as a component for Universal Windows Platform apps. Available on Nuget.
Bauer NC, Yang A, Wang X, Zhou Y, Klibanski A, Soberman RJ. A cross–nearest neighbor/Monte Carlo algorithm for single molecule localization microscopy defines interactions between p53, Mdm2, and MEG3. J Biol Chem. 2021;296:100540. doi:10.1016/j.jbc.2021.100540 [bioRxiv doi:10.1101/857912]
Schmider AB, Bauer NC (co-first), Sunwoo H, Godin MD, Ellis GE, Lee JT, Nigrovic PA, Soberman RJ. Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. J Biol Chem. 2020;295(17):5761-5770. doi:10.1074/jbc.RA119.012069
Schmider AB, Vaught M, Bauer NC, Elliott HL, Godin MD, Ellis GE, Nigrovic PA, Soberman RJ. The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses. PLoS One. 2019;14(2):e0211943. Published 2019 Feb 8. doi:10.1371/journal.pone.0211943
Bauer NC, Corbett AH, Doetsch PW. The current state of eukaryotic DNA base damage and repair. Nucleic Acids Res. 2015;43(21):10083–10101. doi:10.1093/nar/gkv1136
Bauer NC, Doetsch PW, Corbett AH. Mechanisms regulating protein localization. Traffic. 2015;16(10):1039–1061. doi:10.1111/tra.12310
Bauer NC, Corbett AH, Doetsch PW. Automated quantification of the subcellular localization of multicompartment proteins via Q-SCAn. Traffic. 2013;14(12):1200–1208. doi:10.1111/tra.12118